Email: Nicole.delRosso / ucsf, edu
600 16th Street
Genentech Hall, Room N372B
San Francisco, CA 94158
Administrative AssistantGinger Huangginger.huang / ucsf, edu
Nicole received her Ph.D. from the Department of Biophysics at Stanford University in 2024. She worked in the labs of Dr. Lacramioara Bintu and Dr. Polly Fordyce where she discovered hundreds of transcriptional effector domains in human cells and provided the first quantitative map of their disordered interactions with cofactors using a novel microfluidic platform she developed to measure protein-protein binding affinities in high-throughput. The DelRosso Lab at UCSF builds high-throughput techniques to systematically identify molecular interactions that regulate transcription in human cells. They aim to not only understand how disordered proteins recognize their partners to regulate gene expression strength and timing, but also eventually engineer these interactions to enable cellular fate control.