Dr. Masters received a B.A. degree in biology and philosophy from Bowdoin College, and a Ph.D. degree in Physiology and Pharmacology from the University of California, San Diego. Her postdoctoral studies at the University of California, San Francisco explored the molecular mechanisms of G-protein linked signaling. Dr. Masters served as Scientific Director of the UCSF Human Genome Center from 1989 to 1992. In 1993, she joined CMP as a full time educator of UCSF professional students.

She currently directs the IDS 107: Life Cycle course in the new UCSF curriculum, lectures on many topics in pharmacology in other medical and pharmacy courses, and serves on various curriculum committees. She is a member of the Haile T. Debas Academy of Medical Educators.