From Undruggable to Unstoppable: A New Cancer Cure Target Emerges
Roughly a quarter of all cancerous tumors are caused by mutations in the KRAS gene, which fosters cell growth. For more than three decades, scientists believed these mutations were impervious to treatment. Today, National Institutes of Health (NIH)-funded discoveries by UC San Francisco Professor of Cellular Molecular Pharmacology Kevan Shokat, PhD have produced the world’s first drugs that target KRAS.